GenFX^® tablets contain purified amino acids, herbal, plant- and animal-derived constituents. Seven of the amino acids in the tablets are essential amino acids. Essential amino acids are not synthesized in the human body and thus are required to be obtained in the diet, from animal- or plant-derived protein sources. Amino acids are the building blocks of proteins, and GenFX^® provides a total of 12 amino acids to build protein.

Amino acid supplementation may increase body muscle mass and decrease fat deposits (*Dillon et al. 2009). Regulation of nutrient intake and its effects are varied and complex, but it has been shown that an intake of a balanced mixture of amino acids immediately post exercise has anabolic (muscle building) effects (*Biolo et al 1997).

It has been seen that oral intake of L-lysine, L-arginine, and L-ornithine (obtained from L-arginine) can allow athletes to gain muscle mass and strength by increasing growth hormone levels (*Zajac et al. 2010, Chromiak and Antonio 2002). Administration of L-lysine or L-arginine by themselves has proven ineffective, but the combination of equal amounts of lysine and arginine can stimulate growth hormone release from the anterior pituitary (*Isidori et al. 1981). Two other amino acids contained in GenFX, L-glycine and L-glutamine, also play a role in inducing GH secretion in middle-aged and elderly subjects (*Arwert et al. 2003). We have selected these same amino acids, since studies not even investigating the connection between them and HGH have shown them to be an important component to feeling young and healthy.

Of course, we encourage exercise in order to maximize the possibility of obtaining good outcomes, just as the studies show this to be important.

L-Pyroglutamate, or L-pyroglutamic acid, an uncommon amino acid contained in GenFX, has been shown in third party tests to increase cognition by increasing survival of neuronal cells (*Oono et al. 2009). More memory and cognition enhancing effects were shown in studies to be provided by another amino acid constituent, L-tyrosine. L-tyrosine is the substrate for the production of L-Dopa by tyrosine hydroxylase, allowing survival of dopamine signaling neurons.

The plant-based components of GenFX, Panax ginseng powder, derived from the Chinese ginseng plant, contains ginsenosides that enhance alertness and neuronal survival (*Chen et al. 2007), and improve circulation. Soy phosphatide complexes (one being lecithin or phosphatidylcholine) improve brain function and memory, and both phosphatides and phytosterols reduce cholesterol and LDL in plasma (decreasing chances for atherosclerosis) by inhibiting cholesterol uptake in the gut (*Cohn et al. 2010, Sanclemente et al. 2009).

For the animal-based components of GenFX, extracts from bovine anterior pituitary gland contain trace amounts of adrenocorticotropic (ACTH), thyroid-stimulating (TSH), and growth hormones, prolactin, luteinizing hormone, follicle stimulating hormone, endorphins, and melanocyte stimulating hormone. Similarly, hypothalamic extract contains minute amounts of vasopressin and oxytocin. The peptide hormones in these extracts are likely degraded to amino acids by the gastrointestinal tract, serving as substrates for new protein synthesis.

The amino acids and plant phosphatides and phytosterols in GenFX can with exercise and a balanced diet help maintain muscle mass and strength, decrease fat deposits, keep cholesterol and LDL levels at low healthy levels in plasma, and help maintain or improve memory and cognition.